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1.

New Biological Therapies for Multiple Myeloma.

Garfall, Alfred L.

Annu Rev Med; 75: 13-29, 2024 Jan 29.

Artículo en Inglés | MEDLINE | ID: mdl-37729027

2.

Exploiting the CD200-CD200R immune checkpoint axis in multiple myeloma to enhance CAR T-cell therapy.

Tang, Yan; Liu, Wei; Kadu, Siddhant; Johnson, Omar; Hasanali, Zainul S; Kelly, Andre; Shestov, Alexander; Pajarillo, Raymone; Greenblatt, Eli; Holmes, Matthew; Wang, Li-Ping; Shih, Natalie; O'Connor, Roddy S; Ruella, Marco; Garfall, Alfred L; Allman, David; Vogl, Dan T; Cohen, Adam; June, Carl H; Sheppard, Neil C.

Blood; 143(2): 139-151, 2024 Jan 11.

Artículo en Inglés | MEDLINE | ID: mdl-37616575

3.

Teclistamab in Relapsed or Refractory Multiple Myeloma.

Moreau, Philippe; Garfall, Alfred L; van de Donk, Niels W C J; Nahi, Hareth; San-Miguel, Jesús F; Oriol, Albert; Nooka, Ajay K; Martin, Thomas; Rosinol, Laura; Chari, Ajai; Karlin, Lionel; Benboubker, Lotfi; Mateos, Maria-Victoria; Bahlis, Nizar; Popat, Rakesh; Besemer, Britta; Martínez-López, Joaquín; Sidana, Surbhi; Delforge, Michel; Pei, Lixia; Trancucci, Danielle; Verona, Raluca; Girgis, Suzette; Lin, Shun X W; Olyslager, Yunsi; Jaffe, Mindy; Uhlar, Clarissa; Stephenson, Tara; Van Rampelbergh, Rian; Banerjee, Arnob; Goldberg, Jenna D; Kobos, Rachel; Krishnan, Amrita; Usmani, Saad Z.

N Engl J Med; 387(6): 495-505, 2022 08 11.

Artículo en Inglés | MEDLINE | ID: mdl-35661166

4.

Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer.

Akkari, Leila; Gocheva, Vasilena; Quick, Marsha L; Kester, Jemila C; Spencer, Alison K; Garfall, Alfred L; Bowman, Robert L; Joyce, Johanna A.

Genes Dev; 30(2): 220-32, 2016 Jan 15.

Artículo en Inglés | MEDLINE | ID: mdl-26773004

5.

Progressive multifocal leukoencephalopathy in multiple myeloma.

Hoeynck, Brian W; Cohen, Adam D; Stadtmauer, Edward A; Susanibar-Adaniya, Sandra P; Vogl, Dan T; Waxman, Adam J; Bardsley, Mark; Le, Samantha; LaMaestra, Lexis; Garfall, Alfred L.

Eur J Haematol; 110(3): 322-329, 2023 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-36465014

6.

Teclistamab, a B-cell maturation antigenâ×âCD3 bispecific antibody, in patients with relapsed or refractory multiple myeloma (MajesTEC-1): a multicentre, open-label, single-arm, phase 1 study.

Usmani, Saad Z; Garfall, Alfred L; van de Donk, Niels W C J; Nahi, Hareth; San-Miguel, Jesus F; Oriol, Albert; Rosinol, Laura; Chari, Ajai; Bhutani, Manisha; Karlin, Lionel; Benboubker, Lotfi; Pei, Lixia; Verona, Raluca; Girgis, Suzette; Stephenson, Tara; Elsayed, Yusri; Infante, Jeffrey; Goldberg, Jenna D; Banerjee, Arnob; Mateos, María-Victoria; Krishnan, Amrita.

Lancet; 398(10301): 665-674, 2021 08 21.

Artículo en Inglés | MEDLINE | ID: mdl-34388396

7.

Femtomolar SARS-CoV-2 Antigen Detection Using the Microbubbling Digital Assay with Smartphone Readout Enables Antigen Burden Quantitation and Tracking.

Chen, Hui; Li, Zhao; Feng, Sheng; Richard-Greenblatt, Melissa; Hutson, Emily; Andrianus, Stefen; Glaser, Laurel J; Rodino, Kyle G; Qian, Jianing; Jayaraman, Dinesh; Collman, Ronald G; Glascock, Abigail; Bushman, Frederic D; Lee, Jae Seung; Cherry, Sara; Fausto, Alejandra; Weiss, Susan R; Koo, Hyun; Corby, Patricia M; Oceguera, Alfonso; O'Doherty, Una; Garfall, Alfred L; Vogl, Dan T; Stadtmauer, Edward A; Wang, Ping.

Clin Chem; 68(1): 230-239, 2021 12 30.

Artículo en Inglés | MEDLINE | ID: mdl-34383886

8.

Trispecific antibodies offer a third way forward for anticancer immunotherapy.

Garfall, Alfred L; June, Carl H.

Nature; 575(7783): 450-451, 2019 11.

Artículo en Inglés | MEDLINE | ID: mdl-31740852

9.

Chimeric antigen receptor T cell immunotherapy for multiple myeloma: A review of current data and potential clinical applications.

Susanibar Adaniya, Sandra P; Cohen, Adam D; Garfall, Alfred L.

Am J Hematol; 94(S1): S28-S33, 2019 05.

Artículo en Inglés | MEDLINE | ID: mdl-30730071

10.

Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer.

Shree, Tanaya; Olson, Oakley C; Elie, Benelita T; Kester, Jemila C; Garfall, Alfred L; Simpson, Kenishana; Bell-McGuinn, Katherine M; Zabor, Emily C; Brogi, Edi; Joyce, Johanna A.

Genes Dev; 25(23): 2465-79, 2011 Dec 01.

Artículo en Inglés | MEDLINE | ID: mdl-22156207

11.

Chimeric Antigen Receptor T Cells against CD19 for Multiple Myeloma.

Garfall, Alfred L; Maus, Marcela V; Hwang, Wei-Ting; Lacey, Simon F; Mahnke, Yolanda D; Melenhorst, J Joseph; Zheng, Zhaohui; Vogl, Dan T; Cohen, Adam D; Weiss, Brendan M; Dengel, Karen; Kerr, Naseem D S; Bagg, Adam; Levine, Bruce L; June, Carl H; Stadtmauer, Edward A.

N Engl J Med; 373(11): 1040-7, 2015 Sep 10.

Artículo en Inglés | MEDLINE | ID: mdl-26352815

12.

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion.

Gocheva, Vasilena; Wang, Hao-Wei; Gadea, Bedrick B; Shree, Tanaya; Hunter, Karen E; Garfall, Alfred L; Berman, Tara; Joyce, Johanna A.

Genes Dev; 24(3): 241-55, 2010 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-20080943

13.

B-cell maturation antigen chimeric antigen receptor T-cell re-expansion in a patient with myeloma following salvage programmed cell death protein 1 inhibitor-based combination therapy.

Bernabei, Luca; Tian, Lifeng; Garfall, Alfred L; Melenhorst, J Joseph; Lacey, Simon F; Stadtmauer, Edward A; Vogl, Dan T; Gonzalez, Vanessa E; Plesa, Gabriela; Young, Regina M; Waxman, Adam; Levine, Bruce L; June, Carl H; Milone, Michael C; Cohen, Adam D.

Br J Haematol; 193(4): 851-855, 2021 05.

Artículo en Inglés | MEDLINE | ID: mdl-33713436

14.

Axicabtagene ciloleucel for CD19+ plasmablastic lymphoma.

Raychaudhuri, Ruben; Qualtieri, Julianne; Garfall, Alfred L.

Am J Hematol; 95(1): E28-E30, 2020 01.

Artículo en Inglés | MEDLINE | ID: mdl-31725923

15.

Chimeric Antigen Receptor T Cells in Myeloma.

Garfall, Alfred L; Stadtmauer, Edward A; June, Carl H.

N Engl J Med; 374(2): 194, 2016 01 14.

Artículo en Inglés | MEDLINE | ID: mdl-26760100

16.

Chimeric Antigen Receptor T Cells in the Treatment of Multiple Myeloma.

Hasanali, Zainul S; Razzo, Beatrice; Susanibar-Adaniya, Sandra P; Garfall, Alfred L; Stadtmauer, Edward A; Cohen, Adam D.

Hematol Oncol Clin North Am; 38(2): 383-406, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38158242

17.

Human IL-6 fosters long-term engraftment of patient derived disease-driving myeloma cells in immunodeficient mice.

Hasanali, Zainul S; Garfall, Alfred L; Burzenski, Lisa; Shultz, Leonard D; Tang, Yan; Kadu, Siddhant; Sheppard, Neil C; Liu, Wei; Dopkin, Derek; Vogl, Dan T; Cohen, Adam D; Waxman, Adam J; Susanibar-Adaniya, Sandra P; Carroll, Martin; Stadtmauer, Edward A; Allman, David.

JCI Insight; 2024 May 07.

Artículo en Inglés | MEDLINE | ID: mdl-38713510

18.

Efficacy and safety of bendamustine for lymphodepletion before lisocabtagene maraleucel.

Ghilardi, Guido; Paruzzo, Luca; Patel, Vrutti; Svoboda, Jakub; Chong, Emeline R; Fardella, Eugenio; Chong, Elise A; Gabrielli, Giulia; Nasta, Sunita D; Landsburg, Daniel J; Carter, Jordan; Pajarillo, Raymone; Barta, Stefan K; White, Griffin; Weber, Elizabeth; Napier, Ellen; Porter, David L; Garfall, Alfred L; Schuster, Stephen J; Ruella, Marco.

J Hematol Oncol; 17(1): 19, 2024 Apr 22.

Artículo en Inglés | MEDLINE | ID: mdl-38644469

19.

Bendamustine as Lymphodepletion for Brexucabtagene Autoleucel Therapy of Mantle Cell Lymphoma.

Chong, Elise A; Chong, Emeline R; Therwhanger, Dylan; Nasta, Sunita D; Landsburg, Daniel J; Barta, Stefan K; Svoboda, Jakub; Gerson, James N; Ghilardi, Guido; Paruzzo, Luca; Fraietta, Joseph A; Weber, Elizabeth; Stefano, Natalie; Porter, David L; Frey, Noelle V; Garfall, Alfred L; Ruella, Marco; Schuster, Stephen J.

Transplant Cell Ther; 2024 Mar 16.

Artículo en Inglés | MEDLINE | ID: mdl-38494076

20.

Human IL-6 fosters long-term engraftment of patient derived disease-driving myeloma cells in immunodeficient mice.

Hasanali, Zainul S; Garfall, Alfred L; Burzenski, Lisa; Shultz, Leonard D; Tang, Yan; Kadu, Siddhant; Sheppard, Neil C; Dopkin, Derek; Vogl, Dan T; Cohen, Adam D; Waxman, Adam J; Susanibar-Adaniya, Sandra P; Carroll, Martin; Stadtmauer, Edward A; Allman, David.

bioRxiv; 2024 Jan 24.

Artículo en Inglés | MEDLINE | ID: mdl-38328086

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New Biological Therapies for Multiple Myeloma.

Exploiting the CD200-CD200R immune checkpoint axis in multiple myeloma to enhance CAR T-cell therapy.

Teclistamab in Relapsed or Refractory Multiple Myeloma.

Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer.

Progressive multifocal leukoencephalopathy in multiple myeloma.

Teclistamab, a B-cell maturation antigenâ×âCD3 bispecific antibody, in patients with relapsed or refractory multiple myeloma (MajesTEC-1): a multicentre, open-label, single-arm, phase 1 study.

Femtomolar SARS-CoV-2 Antigen Detection Using the Microbubbling Digital Assay with Smartphone Readout Enables Antigen Burden Quantitation and Tracking.

Trispecific antibodies offer a third way forward for anticancer immunotherapy.

Chimeric antigen receptor T cell immunotherapy for multiple myeloma: A review of current data and potential clinical applications.

Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer.

Chimeric Antigen Receptor T Cells against CD19 for Multiple Myeloma.

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion.

B-cell maturation antigen chimeric antigen receptor T-cell re-expansion in a patient with myeloma following salvage programmed cell death protein 1 inhibitor-based combination therapy.

Axicabtagene ciloleucel for CD19+ plasmablastic lymphoma.

Chimeric Antigen Receptor T Cells in Myeloma.

Chimeric Antigen Receptor T Cells in the Treatment of Multiple Myeloma.

Human IL-6 fosters long-term engraftment of patient derived disease-driving myeloma cells in immunodeficient mice.

Efficacy and safety of bendamustine for lymphodepletion before lisocabtagene maraleucel.

Bendamustine as Lymphodepletion for Brexucabtagene Autoleucel Therapy of Mantle Cell Lymphoma.

Human IL-6 fosters long-term engraftment of patient derived disease-driving myeloma cells in immunodeficient mice.